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K Sukegawa Selected Research

Mucopolysaccharidosis IV (Morquio Syndrome)

11/2001Various cells retrovirally transduced with N-acetylgalactosoamine-6-sulfate sulfatase correct Morquio skin fibroblasts in vitro.
2/2001Femoral head dysplasia in Morquio disease type A: bilateral varus osteotomy of the femur.
5/2000Biochemical and structural analysis of missense mutations in N-acetylgalactosamine-6-sulfate sulfatase causing mucopolysaccharidosis IVA phenotypes.
3/2000The mouse N-acetylgalactosamine-6-sulfate sulfatase (Galns) gene: cDNA isolation, genomic characterization, chromosomal assignment and analysis of the 5'-flanking region.

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K Sukegawa Research Topics

Disease

4Mucopolysaccharidosis IV (Morquio Syndrome)
11/2001 - 03/2000
3Mucopolysaccharidoses
10/2007 - 05/2000
1Mucopolysaccharidosis II (Hunter Syndrome)
03/2001
1Type IIIb Gaucher Disease
01/2001
1Liver Diseases (Liver Disease)
01/2001
1Gaucher Disease (Gaucher's Disease)
01/2001

Drug/Important Bio-Agent (IBA)

4SulfatasesIBA
10/2007 - 03/2000
1Complementary DNA (cDNA)IBA
11/2001
1Dermatan SulfateIBA
03/2001
1GlycosaminoglycansIBA
03/2001
1Inositol (Myoinositol)IBA
03/2001
1N-acetylaspartate (N-acetyl aspartate)IBA
03/2001
1Choline (Choline Chloride)IBA
03/2001
1Chondroitin Sulfates (Chondroitin Sulfate)IBA
03/2001
1CreatineIBA
03/2001
1EnzymesIBA
03/2000

Therapy/Procedure

1Bone Marrow Transplantation (Transplantation, Bone Marrow)
03/2001
1Osteotomy
02/2001
1Enzyme Replacement Therapy
01/2001